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目的通过分析2012.10.1-2014.9.30北京市确诊的孕13w-生后1岁内先天性心脏病发生及婴儿期结局情况,为先天性心脏病的防控提供相关信息及依据。方法运用描述性统计学方法回顾性分析北京市出生缺陷监测、婴儿死亡资料。结果 2013-2014年北京市先天性心脏病发病率10.41‰。其中,复杂先天性心脏病(简称CCHD)发病率为1.44‰,构成比13.80%;活产儿中CCHD发病率0.43‰,构成比5.16%;婴儿期病死率19.31%,占CHD婴儿期死亡总数的34.21%。CCHD产前诊断率83.31%,活产患儿中53.46%于出生7天内被检出,此期间内死亡患儿占整个婴儿期死亡71.79%。结论北京市建立的先天性心脏病亚型监测系统,对科学评估不同类型先天性心脏病二级、三级预防效果、探索下一步工作思路提供数据支持;加强对先天性心脏病患儿中染色体异常、临床综合征的排查,对评估本次妊娠预后有重要意义;加强对复杂先天性心脏病新生儿期筛查。
Objective To analyze the incidence of congenital heart disease and infant outcome within 1 year of pregnancy diagnosed in 13 weeks after birth in Beijing from October 10, 2014 to January 14, 2014, and provide relevant information and basis for the prevention and control of congenital heart disease. Methods Descriptive statistics were used to retrospectively analyze the birth defects monitoring and infant mortality data in Beijing. Results The incidence of congenital heart disease in Beijing from 2013 to 2014 was 10.41 ‰. Among them, the incidence of complex congenital heart disease (CCHD) was 1.44 ‰, the ratio of 13.80%; the incidence of CCHD in live births was 0.43 ‰, the ratio of 5.16%; infantile mortality was 19.31%, accounting for the total CHD infants death 34.21%. The prenatal diagnosis rate of CCHD was 83.31%. 53.46% of live births were detected within 7 days of birth, and 71.79% of all infants died during this period. Conclusions The congenital heart disease subtype monitoring system established in Beijing provides data support for scientifically evaluating the secondary and tertiary prevention effects of different types of congenital heart disease and exploring the next working ideas. It is necessary to strengthen the monitoring of chromosomes in children with congenital heart disease Abnormal, clinical syndrome investigation, to assess the prognosis of pregnancy is of great significance; strengthen screening of complex neonatal congenital heart disease.