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目的应用超声技术检测缺血性脑血管病(ICVD)患者颈动脉粥样硬化斑块的临床意义,并对好发部位及狭窄程度性质作以分析。方法应用二维和多普勒血管技术,检测60例缺血性脑血管病患者和20例无脑血管病患者的颈动脉内膜～中膜厚度(IMT)、斑块总积分、斑块总面积及脑血流量。结果二维超声检测结果显示:缺血性脑血管病患者组与对照组比较,颈动脉IMT、斑块总积分、斑块总面积均明显增高,具有显著性差异(P<0.05)。颈总动脉(CCA)、颈内动脉(ICA)、椎动脉(VA)狭窄程度显著高于对照组(P<0.05)。多普勒超声显示,缺血性脑血管病患者的CCA、ICA、VA血流量及脑血流量显著低于对照组(P<0.05)。脑血流量与脑血管疾病的发生呈负相关。结论应用超声技术检测缺血性脑血管病患者的颈动脉粥样硬化和斑块,有助于了解疾病的不同状态以判断病程及预后,对临床上缺血性脑血管病患者的治疗工作具有指导意义。
Objective To detect the clinical significance of carotid artery atherosclerotic plaque in patients with ischemic cerebrovascular disease (ICVD) by using ultrasound and to analyze the characteristics of the site of malignancy and stenosis. Methods Two-dimensional and Doppler vascular techniques were used to detect carotid intima-media thickness (IMT), total plaque score, total plaque score in 60 patients with ischemic cerebrovascular disease and 20 patients without cerebrovascular disease Area and cerebral blood flow. Results The results of two-dimensional ultrasonography showed that IMT, total plaque score and total plaque area of carotid artery in ischemic cerebrovascular disease group were significantly higher than those in control group (P <0.05). Carotid artery (CCA), internal carotid artery (ICA), vertebral artery (VA) stenosis was significantly higher than the control group (P <0.05). Doppler ultrasound showed that the blood flow of CCA, ICA, VA and cerebral blood flow in patients with ischemic cerebrovascular disease were significantly lower than those in the control group (P <0.05). Cerebral blood flow and cerebrovascular disease was negatively correlated. Conclusion The application of ultrasound to detect carotid atherosclerosis and plaque in patients with ischemic cerebrovascular disease helps to understand the different states of the disease to determine the course and prognosis of patients with ischemic cerebrovascular disease in the treatment of patients with Guiding significance.