目的探讨孟鲁司特钠联合丙卡特罗在改善慢性咳嗽症状体征及血清Ig E水平中的作用。方法随机选取镇平县妇幼保健院儿科2012年1月至2015年1月收治的60例慢性咳嗽患儿,依据随机数字表方法分为研究组和对照组,每组30例。对照组采取常规方法以及丙卡特罗治疗,研究组应用常规治疗的用时给予孟鲁司特钠联合丙卡特罗治疗,分析比较两组患儿临床疗效、症状体征及血清Ig E水平改善情况。结果研究组临床有效率高于对照组,且血清Ig E水平、症状体征缓解时间、不良反应方面均显著优于对照组,差异有统计学意义(P<0.05)。结论孟鲁司特钠联合丙卡特罗治疗慢性咳嗽患儿疗效好,可降低患儿血清Ig E水平及不良反应发生率,在改善患儿临床疗效方面发挥积极重要的作用。 Objective To explore the role of montelukast combined with procaterol in improving the signs and serum IgE of chronic cough. Methods A total of 60 children with chronic cough admitted from January 2012 to January 2015 in Zhenping Maternal and Child Health Care Hospital were randomly divided into study group and control group according to random number table method, with 30 cases in each group. The control group was treated with routine method and procaterol. The study group was treated with montelukast sodium and procaterol when routine treatment was used. The clinical efficacy, symptoms and signs and the serum IgE level were compared between the two groups. Results The clinical effective rate was higher in the study group than in the control group, and the level of serum IgE, the time of symptom and symptom relief, adverse reactions were significantly better than the control group, the difference was statistically significant (P <0.05). Conclusion Montelukast combined with procaterol in children with chronic cough has a good curative effect, which can reduce the level of IgE in children and the incidence of adverse reactions, and play an important role in improving the clinical efficacy of children.