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目的:观察国产与进口阿卡波糖联合格列吡嗪治疗2型糖尿病的疗效并比较费用,进行经济学评价。方法:将符合2型糖尿病诊断的患者86例分为A、B两组,A组44例给予国产阿卡波糖,B组42例给予进口阿卡波糖,两组均联合格列吡嗪治疗,统计两组的疗效和降糖药费用,采用最小成本分析方法进行经济学评价。结果:A、B两组的有效率分别为88.6%和90.5%,两组有效率比较无统计学意义(P>0.05);A、B两组的降糖药平均月费用分别为(216.0±15.5)元、(287.1±14.3)元,A组的药品费用明显低于B组(P<0.01)。结论:国产与进口阿卡波糖治疗2型糖尿病疗效无统计学差异,但国产阿卡波糖治疗成本低,是一种经济有效的2型糖尿病治疗方案。
Objective: To observe the effect of domestic and imported acarbose plus glipizide in the treatment of type 2 diabetes mellitus and to compare the cost with the economic evaluation. Methods: Eighty-six patients with type 2 diabetes who were diagnosed as type 2 diabetes were divided into A and B groups, 44 patients in group A were given acarbose, 42 patients in group B were given acarbose, and both were treated with glipizide The curative effect and the cost of hypoglycemic drugs in both groups were statistically analyzed, and the economic evaluation was made by the method of least cost analysis. Results: The effective rates of group A and group B were 88.6% and 90.5% respectively, with no significant difference between the two groups (P> 0.05). The mean monthly cost of hypoglycemic agents in groups A and B were (216.0 ± 15.5) yuan, (287.1 ± 14.3) yuan, the cost of medicine in group A was significantly lower than that in group B (P <0.01). Conclusion: The domestic and imported acarbose treatment of type 2 diabetes no significant difference in efficacy, but the domestic acarbose low cost of treatment is a cost-effective treatment of type 2 diabetes.