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目的通过对轻重型急性脑梗死患者一般临床资料、血清生化指标对比研究,分析不同病情脑梗死患者的临床特征,探讨对急性脑梗死早期诊断、危险分层有临床价值的指标,分析各指标之间的相关性,提高脑梗死的诊治水平。方法法收集发病7天内住院的急性脑梗死患者430例,按照NIHSS评分分为轻、重型脑梗死,对两组临床资料及生化指标进行比较,各指标之间采用Spearman相关分析,脑梗死危险因素分析采用二分类Logistic回归分析。结果多因素回归分析结果显示:HUA、LDL、WBC是重型脑梗死的独立危险因素。结论血清LDL、UA、WBC计数与脑梗死发生、发展密切相关,对脑梗死早期危险分层及预后评估有一定的指导意义,应尽早综合评估各项指标。
Objective To compare the clinical data of patients with severe acute and severe acute cerebral infarction and serum biochemical indexes to analyze the clinical characteristics of patients with cerebral infarction in different conditions and to explore the clinical value of early diagnosis and risk stratification of acute cerebral infarction, Between the correlation and improve the diagnosis and treatment of cerebral infarction. Methods A total of 430 hospitalized acute cerebral infarction patients within 7 days after onset were collected and divided into mild and severe cerebral infarction according to NIHSS score. The clinical data and biochemical indexes were compared between the two groups. Spearman correlation analysis, risk factors of cerebral infarction Analysis using binary Logistic regression analysis. Results Multivariate regression analysis showed that HUA, LDL and WBC were independent risk factors for severe cerebral infarction. Conclusions The serum LDL, UA and WBC counts are closely related to the occurrence and development of cerebral infarction. It is of guiding significance in early stage of risk stratification and prognosis evaluation of cerebral infarction. All indexes should be evaluated comprehensively as soon as possible.