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目的:为了及时动态掌握烧伤病人感染菌生态学及药敏情况。方法:收集我科1994年~1997年烧伤创面分泌物,各种导管插管,血液标本226份进行细菌学调查。结果:细菌培养阳性138份(58.8%),其中创面分泌物送检160份,阳性120份(75%),导管插管标本40份,阳性10份(25%),血液标本26份,阳性8份(30.8%);共检出细菌14种153株,耐甲氧西林金葡菌高居第一位,占23.5%,绿脓杆菌次之,占17.6%。药敏结果提示:耐甲氧西林金葡菌对去甲万古霉素最敏感(100%),其次为环丙沙星(87.7%),其它均耐药;革兰氏阴性杆菌对舒普深、复达欣耐药率最低。结论:耐甲氧西林金葡菌已取代绿脓杆菌上升为第一位优势菌,且只对去甲万古霉素,环丙沙星敏感。
Objective: To timely and dynamically learn the ecology and drug sensitivity of infected patients. Methods: Bacteriological investigations were conducted on 226 specimens from the burn wounds of our department from 1994 to 1997, including catheter intubation and blood samples. Results: 138 (58.8%) samples were positive for bacterial culture, of which 160 were for examination of wound secretions, 120 were positive (75%), 40 were catheter cannulae, 10 were positive (25%), and 26 were blood specimens. 8 (30.8%) were positive. A total of 14 strains of 153 strains were detected. The methicillin-resistant Staphylococcus aureus ranked first, accounting for 23.5%, and Pseudomonas aeruginosa followed, accounting for 17.6%. Drug susceptibility results suggest that methicillin-resistant Staphylococcus aureus is the most sensitive to norvancomycin (100%), followed by ciprofloxacin (87.7%), all other resistance; Gram-negative bacilli to Shu Pu deep, complex Daxin has the lowest resistance rate. CONCLUSIONS: methicillin-resistant S. aureus has replaced P. aeruginosa as the dominant bacterium, and it is only sensitive to norvancomycin and ciprofloxacin.