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目的:探讨硝普钠治疗顽固性心衰的疗效。方法:选取2005-12/2008-12 100例顽固性心衰患者,随机分成两组,均予强心、利尿、扩血管等对症常规治疗。治疗组对血压正常的患者硝普钠与多巴胺量按1∶2比例配置。加入生理盐水10 ml,应用微量泵,2 ml/h泵入,避光,6 h更换。对血压高的患者,应用微量泵泵入硝普钠25 mg+生理盐水10 ml,2 ml/h开始,根据血压调速度,5 d为1个疗程,心衰控制后减量至停用。结果:治疗组总有效率96%,对照组治疗总有效率62%。治疗组有效率高于对照组。结论:硝普钠联合多巴胺治疗顽固性心衰临床有效,不良反应少,值得基层医院推广。
Objective: To investigate the curative effect of sodium nitroprusside on refractory heart failure. Methods: One hundred patients with refractory heart failure from Dec 2005 to Dec 2008 were randomly divided into two groups. All patients were given symptomatic treatment such as cardiotomy, diuretic and vasodilatation. The treatment group of normal blood pressure in patients with sodium nitroprusside and dopamine dose ratio of 1: 2 configuration. Add 10 ml of saline solution, apply a micro pump, pump 2 ml / h, protect from light and replace for 6 h. Patients with high blood pressure, the use of micropump pump into the sodium nitroprusside 25 mg + saline 10 ml, 2 ml / h start, according to blood pressure speed, 5 d for a course of treatment, heart failure control to reduce to disable. Results: The total effective rate was 96% in the treatment group and 62% in the control group. The treatment group was more effective than the control group. Conclusion: Sodium nitroprusside combined with dopamine treatment of refractory heart failure clinical effective, less adverse reactions, it is worth promoting the primary hospital.