绒毛取样(CVS)已广泛应用于孕早期的产前诊断。曾有作者报道可能发生胎儿肢体缺损,推测其机理认为CVS检测可能损伤血管影响胎儿血流,发生血栓、血管收缩、心动过缓、导致血流灌注不足。彩色血流多普勒仪在孕早期能检测到胎儿脐血流情况。研究假定因CVS损伤了胎儿脐血流而影响到胎儿,可以在操作前后及时通过多普勒监测这些变化。 Villus sampling (CVS) has been widely used in prenatal diagnosis of early pregnancy. Some authors have reported that fetal limb defects may occur, suggesting that the mechanism that the CVS test may damage the blood vessels affect fetal blood flow, thrombosis, vasoconstriction, bradycardia, resulting in inadequate perfusion. Color flow Doppler in early pregnancy can detect fetal umbilical blood flow. The study hypothesized that these changes were monitored by Doppler before and after the operation, assuming that CVS impaired fetal umbilical flow and affected the fetus.