枳实为传统中药,具有兴奋或抑制胃肠道平滑肌的作用,临床用于治疗胃肠道及心血管类疾病。黄酮类化合物是其主要的活性组分之一,量较高。讨论了枳实中二氢黄酮类成分体内外吸收代谢以及对其他药物的影响,以进一步了解其功效机制以及药物配伍时的相互作用,为提高枳实活性成分在体内的生物利用度,增强疗效提供研究基础。 Citrus aurantium as a traditional Chinese medicine, with the excitement or inhibition of gastrointestinal smooth muscle function, the clinical treatment of gastrointestinal and cardiovascular diseases. Flavonoids is one of the main active components, the amount is high. In this paper, we discussed the absorption and metabolism of flavonoids in Fructus Aurantii (Fructus Aurantii Immaturus) in vitro and in vivo as well as their effects on other drugs in order to further understand the mechanism of action and the interaction between flavonoids. To improve the bioavailability of active ingredients in Fructus Aurantii Provide the basis of research.