论文部分内容阅读
目的弹性应变率比值法在乳腺癌新辅助化疗疗效评价中的应用价值。方法选取51例我院乳腺外科行新辅助化后,并手术治疗的女性乳腺癌患者,根据化疗前后乳腺癌肿块弹性应变率比值的变化进行疗效评价,与临床疗效评价结果运用SPSS 16.0进行对比分析。结果 51例乳腺癌NAC前后,超声弹性检查与临床疗效评价标准参照,其灵敏度、特异度、准确度为86.4%、71.4%、84.3%,一致性检验Kappa值为0.466。结论 (1)51例患者经超声检查,其病灶弹性应变率比值在NAC前后的变化具有显著性差异。(2)超声弹性应变率比值法与临床疗效评价有中高度的一致性,在乳腺浸润性导管癌NAC疗效评价中具有较好的应用价值。
The purpose of the elastic strain rate ratio in the evaluation of the efficacy of neoadjuvant chemotherapy for breast cancer. Methods Fifty-one female breast cancer patients who underwent neoadjuvant surgery and were treated surgically were enrolled in this study. The curative effect was evaluated according to the ratio of the elastic strain rate before and after chemotherapy. The results were compared with the results of clinical evaluation using SPSS 16.0 . Results The sensitivity, specificity and accuracy of ultrasound elastography and clinical evaluation of 51 cases of breast cancer before and after NAC were 86.4%, 71.4% and 84.3%, respectively. The consistency test Kappa value was 0.466. Conclusions (1) 51 cases of patients by ultrasound examination, the lesion elastic strain rate ratio before and after NAC changes significantly. (2) There is a high degree of consistency between the ultrasound elastic strain rate ratio method and clinical curative effect evaluation, and it has a good value in the evaluation of NAC in breast invasive ductal carcinoma.