Concomitant hepatocellular adenoma and adenomatous hyperplasia in a patient without cirrhosis

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:qwertyuiopgfdsa
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AIM Hepatocelluar adenoma(HCA)and adenomatoushyperplasia(AH)are rare benign tumors of the liver.HCA isusually found in women who use oral contraceptives.AHusually occurs in patients with liver cirrhosis.Both tumorshave potential for malignant transformation.METHODS:We described a male adult with chronic liverdisease(CLD)who had been known to be a hepatitis Bcarrier(HBV)for years.He was found to have a space-occupying lesion with a suspidon of hepatocellular carcinoma(HCC)by abdominal ultrasonography.His a-fetoprotein(AFP)was normal.Angiographic findings were consistent with thediagnosis of HCC,he wished to avoid an operation,wastreated with transcatheter hepatic arterial embolization.RESULTS:He subsequently consented to surgery,and aright Iobectomy was performed.The liver pathology disclosedHCA with nuclear dysplasia and post-embolization effects.In addition,there were multiple small foci of AH with nucleardysplasia in the resected liver.Although he had some focalareas of cirrhosis-like change or post-embolization effect,the AH was associated only with normal liver tissue.CONCLUSION:This case confirms that HCA and AH mayresemble HCC on imaging studies,and that AH may occurin CLD in the absence of cirrhotic change. AIM Hepatocelluar adenoma (HCA) and adenomatous hyperplasia (AH) are rare benign tumors of the liver. HCA is usually found in women who use oral contraceptives. AHusually occurs in patients with liver cirrhosis. Both tumorshave potential for malignant transformation. METHODS: We described a male adult with chronic liver disease (CLD) who had been known to be hepatitis Bcarrier (HBV) for years. He was found to have a space-occupying lesion with a suspidon of hepatocellular carcinoma (HCC) by abdominal ultrasonography. His a-fetoprotein AFP) was normal. Angiographic findings were consistent with the diagnosis of HCC, he wished to avoid an operation, wastreated with transcatheter hepatic arterial embolization .RESULTS: He subsequently consented to surgery, and aright Iobectomy was performed.The liver pathology disclosedHCA with nuclear dysplasia and post-embolization effects.In addition, there were multiple small foci of AH with nucleardysplasia in the resected liver .Although he had some focalareas of cirrhosis-lik The change was either post-embolization effect, the AH was associated only with normal liver tissue. CONCLUSION: This case confirms that HCA and AH mayresemble HCC on imaging studies, and that AH may occur in CLD in the absence of cirrhotic change.
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