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结缔组织疾病是指一组病因未明的类风湿疾病。本文所述包括类风湿关节炎,系统性红斑狼疮(SLE),进行性系统系硬化症(PSS或称硬皮病),典型的结节性多动脉炎(PAN),多发性肌炎(皮肌炎),强直性脊椎炎,以及尿道-关节-结膜综合征。这些疾病最显著的典型症状是累及关节和皮肤。但也可发生心脏病,这对决定患者是否患有慢性或致命性疾病,起着重要的作用。本病的心脏症状和体征可继发于其他部位的病变。肺血管炎和纤维化,可导致肺高压、肺心病(PSS及SLE)和右心衰竭。由于肾功能不全所造成的高血压,可引起左心衰竭
Connective tissue disease is a group of rheumatoid diseases of unknown etiology. Described herein include rheumatoid arthritis, systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS or scleroderma), typical polyarteritis nodosa (PAN), polymyositis Myositis), ankylosing spondylitis, and urinary tract-joint-conjunctival syndrome. The most prominent symptoms of these diseases are the joints and the skin. But heart disease can also occur, which plays an important role in determining whether a patient has a chronic or fatal disease. The symptoms and signs of the heart disease may be secondary to other parts of the lesion. Pulmonary vasculitis and fibrosis can lead to pulmonary hypertension, cor pulmonale (PSS and SLE) and right heart failure. As a result of renal insufficiency caused by hypertension, can cause left heart failure