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目的:观察中西医结合防治冠心病支架术(PCI)后再狭窄的效果。方法:将88例PCI术后患者按随机数字表法分为对照组与观察组各44例,对照组接受西药防治PCI术后再狭窄,观察组则采用中西医结合预防方案,在对照组用药基础上加用自拟益心通脉汤,比较2组术后6月支架内再狭窄发生率,观察用药前后患者中医证候积分的变化。结果:总有效率观察组为93.18%,对照组为72.73%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组中医证候总积分比较,差异无统计学意义(P>0.05)。治疗后,观察组中医证候积分较治疗前降低,并低于对照组,差异均有统计学意义(P<0.05)。再狭窄率观察组为9.09%,对照组为43.18%,2组比较,差异有统计学意义(P<0.01)。结论:在PCI术后再狭窄的防治中采用中西医联合方案,可降低再狭窄率,改善患者的中医证候,优化临床治疗效果,推广价值高。
Objective: To observe the effect of integrated traditional Chinese and western medicine on prevention of restenosis after coronary stenting (PCI). Methods: Eighty-eight patients undergoing PCI were divided into control group and observation group according to random number table method, 44 patients in each group. The control group received western medicine to prevent and treat the restenosis after PCI. The observation group received the combined traditional Chinese and western medicine prophylaxis. In the control group, Based on the addition of self-made Yixintongmai soup, the incidence of in-stent restenosis was compared between the two groups in June and the changes of TCM syndrome scores before and after treatment were observed. Results: The total effective rate was 93.18% in the observation group and 72.73% in the control group. There was significant difference between the two groups (P <0.05). Before treatment, there was no significant difference between the two groups in the total score of TCM syndromes (P> 0.05). After treatment, the scores of TCM syndromes in observation group were lower than those before treatment, and the differences were statistically significant (P <0.05). Restenosis rate was 9.09% in the observation group and 43.18% in the control group. There was significant difference between the two groups (P <0.01). Conclusion: The combination of Chinese and Western medicine in the prevention and treatment of restenosis after PCI can reduce the rate of restenosis, improve the TCM syndromes of patients and optimize the effect of clinical treatment, so the value of popularization is high.