目的:研究分析肿瘤标志物检验应用在肺癌检验与诊断结果的评价。方法:对在我院就诊的59例患者,依照穿刺病理或经手术确诊为肺癌患者以及确诊为肺良性疾病患者分为A组和B组,各33例、26例,并在同期选取20例正常体检者作为C组,对3组研究对象血清肿瘤标志物进行检测。结果:A组患者的肿瘤标志物(NSE、CEA和CYFRAZI-1以及CA125)水平结果明显高于B组和C组,而后两组的血清肿瘤标志物水平结果的比较均无存在差异;单项检测与联合检测的准确度及灵敏度存在着差异,而在联合检测与其他4个单项检测的特异度均无明显差异。结论:肿瘤标志物对肺癌的检测与诊断结果有着积极的作用,可为肺癌的诊断提供了依据,联合检测对肺癌诊断的准确度、灵敏度有进一步的提高。 Objective: To study and evaluate the application of tumor marker test in lung cancer test and diagnosis. Methods: Fifty-nine patients treated in our hospital were divided into group A and group B according to the biopsy or surgical diagnosis of lung cancer and diagnosed as benign pulmonary diseases, 33 cases and 26 cases each, and 20 cases were selected at the same period Normal subjects as C group, three groups of serum tumor markers were detected. Results: The levels of tumor markers (NSE, CEA and CYFRAZI-1 and CA125) in group A were significantly higher than those in groups B and C, but there was no difference in serum tumor marker level between the two groups. There were differences with the accuracy and sensitivity of the joint detection, but there was no significant difference between the combined detection and the other four single detection. Conclusion: Tumor markers have a positive effect on the detection and diagnosis of lung cancer, which can provide a basis for the diagnosis of lung cancer. The accuracy and sensitivity of the combined detection for the diagnosis of lung cancer are further improved.