论文部分内容阅读
目的了解住院腹泻患者艰难梭菌带菌情况,为抗生素相关腹泻患者的诊断和治疗提供参考。方法收集2015年9月至2016年8月住院腹泻患者粪便标本163份,用艰难梭菌快速检测试剂盒检测艰难梭菌。结果艰难梭菌检出总阳性率为20.86%(34/163),其中春季16.67%、夏季15.79%、秋季17.86%、冬季27.87%,经比较差异无统计学意义(χ2=2.943,P>0.05);成人粪便标本阳性率为22.52%(25/111),儿童粪便标本阳性率为17.31%(9/52),差异无统计学意义(χ2=0.583,P>0.05);男性粪便标本阳性率为21.69%(18/83),女性粪便标本阳性率为20.0%(16/80),差异无统计学意义(χ2=0.202,P>0.05);艰难梭菌阳性患者抗菌药物平均使用天数为12.74d,阴性患者为8.21d,差异有统计学意义(t=-7.81,P<0.01)。结论住院腹泻患者艰难梭菌阳性率高低与抗菌药物使用时间长短有关。
Objective To understand the infection of C. difficile in hospitalized diarrhea patients and provide reference for the diagnosis and treatment of patients with antibiotic-associated diarrhea. Methods A total of 163 stool specimens from hospitalized patients with diarrhea in hospital from September 2015 to August 2016 were collected. Clostridium difficile was detected with a Clostridium difficile rapid test kit. Results The positive rate of Clostridium difficile was 20.86% (34/163), of which 16.67% in spring, 15.79% in summer, 17.86% in autumn and 27.87% in winter, the difference was not statistically significant (χ2 = 2.943, P> 0.05 ). The positive rate of adult stool specimens was 22.52% (25/111), and the positive rate of stool specimens was 17.31% (9/52) in children (χ2 = 0.583, P> 0.05). The positive rate of male stool specimens The positive rate of antibacterials in positive C. difficile was 12.74 (18/83), and the positive rate of female stool specimens was 20.0% (16/80), with no significant difference (χ2 = 0.202, P> 0.05) d, the negative patients was 8.21d, the difference was statistically significant (t = -7.81, P <0.01). Conclusions The positive rate of Clostridium difficile in hospitalized diarrhea is related to the duration of antimicrobial use.