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1978年6月至1993年10月我院收治44例卵巢颗粒细胞瘤。其中41例为首次治疗,3例为复发后治疗。36例作根治性手术,22例加放射治疗,21例作抗癌化疗1~7疗程;32例治疗已满5~17年,5年生存率81.2%。其中I期100%(23/23),Ⅱ期60%(3/5),Ⅲ、Ⅳ期均为零(0/2,0/2)。2例保留健侧卵巢和子宫的年青患者,已结婚生育。本文对保留生育功能、根治性手术及术后放疗、化疗、5年生存率等问题进行分析讨论。
From June 1978 to October 1993, 44 cases of ovarian granulosa cell tumor were treated in our hospital. Among them, 41 cases were treated for the first time and 3 cases were treated for recurrence. Twenty-six patients underwent radical surgery. Twenty-two patients received radiotherapy and 21 patients received anticancer chemotherapy for one to seven cycles. 32 patients were treated for 5 to 17 years and the 5-year survival rate was 81.2%. Among them, 100% (23/23) in stage I, 60% (3/5) in stage II, and 0/2/0/2 in stage III and IV. Two young patients who retained the contralateral ovary and the uterus were married and fertile. This article analyzes and discusses the issues such as retention of fertility, radical surgery and postoperative radiotherapy, chemotherapy, and 5-year survival rate.