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目的:分析心脑血管类中药注射剂不良反应的特点、规律及影响因素。方法:采用回顾性分析的方法,对我院2006—2007年收集到的42例心脑血管类中药注射剂不良反应报告,从患者年龄、药品种类、给药途径、累及系统-器官以及临床表现等方面进行统计、分析。结果:42例心脑血管类中药注射剂不良反应涉及的系统-器官以皮肤及附件损害发生频率最高,占30.16%;因联合用药所致的不良反应为其主要原因。结论:临床中应严格按照说明书适应症及用法、用量规定用药,应注意药物间相互作用,避免不合理用药,以保障临床用药安全、有效。
Objective: To analyze the characteristics, regularity and influencing factors of adverse reactions of cardiovascular medicine injection. Methods: A retrospective analysis of the hospital from 2006 to 2007 collected 42 cases of cardiovascular and cerebrovascular injection of adverse reactions reported from the patient’s age, type of drug, route of administration, systemic-organ involvement, and clinical manifestations Statistics, analysis. Results: 42 cases of cardiovascular and cerebrovascular medicine injection adverse reactions involving the system - organs with the highest frequency of skin and accessory damage, accounting for 30.16%; adverse reactions due to combination therapy is the main reason. Conclusion: The clinical application should be strictly in accordance with the indications and usage instructions, dosage prescribed medication, should pay attention to drug interactions, to avoid irrational medication, in order to protect clinical drug safety and effectiveness.