【摘 要】
：
恶性肿瘤的发生、发展是一个受多种外界致癌因素作用导致多种遗传学改变并逐渐积累的过程。病毒是许多恶性肿瘤的重要诱因 ,因而病毒基因结构与功能的研究一直是恶性肿瘤病因
【机 构】
：
中南大学湘雅医学院肿瘤研究所!湖南长沙410078,中南大学湘雅医学院肿瘤研究所!湖南长沙410078
【出 处】
：
国外医学(生理、病理科学与临床分册)
论文部分内容阅读
恶性肿瘤的发生、发展是一个受多种外界致癌因素作用导致多种遗传学改变并逐渐积累的过程。病毒是许多恶性肿瘤的重要诱因 ,因而病毒基因结构与功能的研究一直是恶性肿瘤病因发病学研究领域中的焦点。EB病毒与许多人类恶性疾病的发生密切相关。本综述就EB病毒基因结构与功能的关系、EB病毒进入细胞的机制、EB病毒相关的动物模型的建立等方面作一较为详细的阐述。
The occurrence and development of malignant tumor is a process of multiple genetic changes and gradual accumulation by a variety of external carcinogenic factors. Viruses are an important inducer of many malignant tumors. Therefore, the study on the structure and function of viral genes has been the focus in the field of etiology of malignant tumors. Epstein-Barr virus is closely related to the occurrence of many human malignancies. This review provides a more detailed description of the relationship between the structure and function of Epstein-Barr virus genes, the mechanism of Epstein-Barr virus entering the cell, and the establishment of an animal model of Epstein-Barr virus.
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