草鱼出血病是一种病毒性疾病,而免疫防治是该病最有效的防治方法之一,因此疫苗研制对该病的防治意义重大。多年来鱼用疫苗制品为组织灭活疫苗,但它要在发病季节从自然界收集材料,因而几乎不可能大批量生产,往往冬末春初放养草鱼种期间因缺乏疫苗而错过了预防免疫时机。采用离体细胞培养法制备疫苗就能克服上述缺点。近年来国内一些研究单位利用 Grass carp hemorrhagic disease is a viral disease, and immune prevention and treatment is one of the most effective prevention and treatment of the disease, so vaccine development is of great significance for the prevention and treatment of the disease. Fish vaccine products have been used as tissue inactivation vaccines for many years. However, they have to be collected from nature during the disease season, making it almost impossible for them to be mass-produced. In the late winter and early spring, the timing of immunization was missed due to lack of vaccines. The use of in vitro cell culture vaccine can overcome the above shortcomings. In recent years, some domestic research institutes use