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通过多种动物(特别是大鼠)的实验,已公认多巴胺具有催乳素抑制因子的作用。在人类,经在体点滴多巴胺也证实了对催乳素分泌的抑制作用,但是,上述在人类的观察多采用超生理剂量(点滴速率为2～7μg/kg·分钟)的多巴胺进行点滴,这样观察到的多巴胺对催乳素分泌的抑制作用,其生理意义值得怀疑。多巴胺作为一种催乳素抑制因子的调节作用也具有病理意义,有作者提出,催乳素瘤的产生与催乳素分泌的中枢多巴胺调控缺陷有
It has been recognized that dopamine acts as a prolactin inhibitory factor by experiments with various animals, especially rats. Doping with dopamine in the body also confirmed the inhibitory effect on prolactin secretion, however, the above observation in humans using dopamine at a super-physiological dose (instillation rate of 2 to 7 μg / kg · min) To dopamine on prolactin secretion inhibition, its physiological significance is questionable. The role of dopamine as a regulator of prolactin inhibition also has pathological significance, the authors suggest that the prolactinoma and prolactin secretion of central dopamine regulatory defects