妊娠期间感染疟疾,特别是恶性疟,可使病情加重,并威协母子双方的生命。在流行地区是低体重儿、胎儿假死、死产、早产的主要原因。为此,作者通过伯氏鼠疟原虫诱发急性疟疾,以研究其对小鼠胚或胎仔发育的影响。实验使用传代的伯氏鼠疟原虫NK 65和BALB/c小鼠,出生后第4周雌雄分别饲养,第10～14周取雄鼠1只,雌鼠2～4只并笼交配。每天观察阴部2次,以形成阴道栓的日期作为妊娠0日。使用12～14周龄、20 Infection during pregnancy malaria, especially falciparum malaria, can aggravate the disease, and Wei co-mother and son on both sides of life. In endemic areas are low birth weight children, fetal suspended animation, stillbirth, the main reason for premature delivery. To this end, the authors induced acute malaria by P. berberis to study its effect on mouse embryo or fetal development. Experiments using the passage of P. berberis NK 65 and BALB / c mice, the first 4 weeks after birth were housed male and female, the first 10 to 14 weeks to take a male mouse, female mouse 2 to 4 and cage mating. 2 times a day to observe the genitals, vaginal suppository to form the date as pregnancy 0. Use 12 to 14 weeks of age, 20