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目的:观察疏血通注射液联合维生素E胶丸治疗不稳定型心绞痛的临床疗效。方法:将50例患者随机分为对照组和治疗组,对照组24例采用西医常规治疗及疏血通注射液,治疗组26例在对照组治疗基础上加用维生素E胶丸。观察治疗前后心绞痛发作频率、发作间期、持续时间、Holter24h缺血总时间、ST下移、心肌耗氧指数等以评价其疗效。结果:总有效率治疗组为88.5%,对照组为66.7%,2组比较,差异有显著性意义(P<0.05)。治疗组治疗后心绞痛发作频率、发作间期、持续时间均显著改善,与治疗前比较,差异均有非常显著性意义(P<0.01)。对照组治疗后心绞痛发作频率、发作间期、持续时间也有一定改善,与治疗前比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。2组治疗后各指标比较,差异也有显著性意义(P<0.05)。2组治疗后Holter 24h缺血总时间、ST下移、T波倒置、心肌耗氧指数均显著改善,与治疗前比较,差异有显著性或非常显著性意义(P<0.01,P<0.05)。2组治疗后比较,Holter 24h缺血总时间、心肌耗氧指数差异也有显著性意义(P<0.05)。结论:疏血通注射液联合维生素E胶丸治疗不稳定型心绞痛疗效肯定。
Objective: To observe the clinical effect of Shuxuetong injection combined with vitamin E capsules in the treatment of unstable angina pectoris. Methods: Fifty patients were randomly divided into control group and treatment group, 24 cases in control group were treated with conventional western medicine and Shuxuetong injection. The treatment group was given vitamin E capsules on the basis of the control group. Before and after treatment angina pectoris frequency, duration of attack, duration of Holter24h ischemia, ST down, myocardial oxygen consumption index to evaluate its efficacy. Results: The total effective rate was 88.5% in the treatment group and 66.7% in the control group. There was significant difference between the two groups (P <0.05). The frequency of angina pectoris, duration of seizure and duration of treatment in treatment group were significantly improved after treatment, which were significantly different from those before treatment (P <0.01). The frequency of angina pectoris, duration of seizure and duration of treatment in control group also improved to some extent. There was significant or very significant difference between the two groups (P <0.05, P <0.01). There was also significant difference between the two groups after treatment (P <0.05). The total ischemia 24h time, ST down shift, T wave inversion and myocardial oxygen consumption index in Holter 24h group were significantly improved after treatment (P <0.01, P <0.05), and there was significant difference between before and after treatment . After treatment, Holter 24h ischemic total time, myocardial oxygen consumption index also had significant difference (P <0.05). Conclusion: Shuxuetong injection combined with vitamin E capsules for the treatment of unstable angina pectoris sure effect.