食管,贲门上皮重度增生细胞(重增),每年自然转归趋势大体相似。蔡氏报道的1974～1977年的215例自然好转率为29.8％,病变率为7.4％。我们采用维酶素对143例重增病例进行了治疗,平均3年半,好转率为61.5％,癌变率为1.4％各地报道的重增检出率大都在3～5％左右,我们采用“三上三下”的拉 Esophageal, cardiac hyperplasia of severely hyperplastic epithelium (re-increase), the natural outcomes are roughly similar each year. According to Chua’s report, the natural improvement rate of 215 cases from 1974 to 1977 was 29.8%, and the lesion rate was 7.4%. We used riboflavin to treat 143 cases of heavy increase, an average of 3 and a half years, the improvement rate was 61.5%, and the cancerous rate was 1.4%. The rate of increase in coverage reported in most cases was around 3 to 5%. We used " Three up and three down