Barrett′s Esophagus(简称BE)是食管下段复层鳞状上皮被单层柱状上皮替代的病理现象。1950年Barrett首先观察到此现象,近年来认识到,BE属于食管粘膜的胃、肠上皮化生性变化,与食管腺癌的发生有密切关系,是食管腺癌的一种癌前病变,在国外已受到普遍重视。发病率:BE并非少见。常规尸检中发现率12%,反流性食管炎患者中发生率约11%,成人9.1%,儿童13%。发病年龄自生后1月至92岁均有报告,0～15岁,48～80岁是双高峰,多数人中年以后因发生并发症而被确诊。病因:先天性学说认为,出生前来源 Barrett’s Esophagus (BE) is a pathological phenomenon in which the lower esophageal squamous epithelium is replaced by a single columnar epithelium. Barrett first observed this phenomenon in 1950, in recent years recognized that BE belongs to the esophageal mucosa of the stomach, intestinal metaplasia changes, and the occurrence of esophageal adenocarcinoma is closely related to esophageal adenocarcinoma is a precancerous lesions in foreign countries Has received universal attention. Incidence: BE is not uncommon. Regular autopsy was found in 12% of patients with reflux esophagitis incidence of about 11%, 9.1% of adults, children 13%. The age of onset from January 1 to 92 years of age have been reported, 0 to 15 years old, 48 to 80 years old is a double peak, most people were diagnosed due to complications after middle age. Etiology: Congenital doctrine that before birth source