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鼻咽癌所致脑脊液漏是一种罕见的临床表现,我院收治2例,报告如下: 例1,男,54岁,1984年6月29日入院。右鼻孔溢液,鼻阻5~+月,双侧头痛、鼻衄3月。溢液量每日约100ml,水样透明。否认头颅外伤及脑膜炎病史。检查见:右鼻孔有淡黄色透明液体流出,鼻咽部见鼻咽右侧壁及右鼻后孔新生物。无颅神经受损体征,脑膜刺激征(-),颈淋巴结(-)。X光片示鼻咽右侧壁及右鼻腔软组织影,鼻中隔后伤及右侧卵圆孔骨质破坏。鼻咽部病理活检:低分化癌。右鼻孔溢出液化验:淡黄色,微浑,蛋白强阳性,糖40—50mg%,考虑为脑脊液。腰穿注入酚红后右鼻孔溢出液逐渐变
The cerebrospinal fluid leakage caused by nasopharyngeal carcinoma is a rare clinical manifestation. There are 2 cases in our hospital. The report is as follows: Case 1, male, 54 years old, admitted to hospital on June 29th, 1984. Right nostril discharge, nasal obstruction 5 to + months, bilateral headache, nasal discharge in March. The daily amount of liquid is about 100ml and the water sample is transparent. Denied the history of head trauma and meningitis. For inspection see: The right nostril has a pale yellow transparent liquid, and the nasopharyngeal sees the right side of the nasopharyngeal wall and the right nasal orifice. No sign of cranial nerve damage, meningeal irritation sign (-), cervical lymph node (-). The X-ray film shows the soft tissue of the right side wall of the nasopharyngeal and the right nasal cavity. After the nasal septum, it damages the bone of the right foramen ovale. Nasopharyngeal biopsy: poorly differentiated cancer. Right nostril spilt fluid assay: light yellow, slightly blistered, strongly protein positive, sugar 40-50 mg%, considered cerebrospinal fluid. After the lumbar puncture was injected with phenol red, the right nostril overflow gradually changed