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目的探讨同种异体皮覆盖急性毁损性创面,提高患者救治成功率及促进创面愈合的可行性。方法 回顾性分析56例急诊住院治疗皮肤软组织严重毁损性患者的临床病例,按治疗方法分组:急诊清创后同种异体皮覆盖创面,待二期修复创面的28例为治疗组;清创后一期皮瓣、植皮封闭创面的28例设为对照组,观察两组患者的救治成功率和创面封闭时间。结果 两组救治成功率分别为96.43%和78.57%,差异具有统计学意义(P<0.05);实验组创面治愈时间(16.17±1.87)d与实验组(21.71±3.95)d,差异具有统计学意义(P<0.01)。结论 皮肤软组织严重毁损性损伤急诊手术应以稳定患者全身情况为重点,创面使用同种异体皮覆盖待二期修复,可降低急诊手术的风险性,提高患者救治成功率,缩短治疗周期。
Objective To investigate the feasibility of allogeneic skin covering acute and destructive wounds, improving the success rate of patients and promoting wound healing. Methods A retrospective analysis of 56 cases of emergency hospitalized patients with severe soft tissue degeneration and clinical cases were grouped according to the method of treatment: emergency debridement after allogeneic skin covering wounds, two to be repaired wounds 28 cases for the treatment group; after debridement A flap, skin graft closed 28 cases as a control group, the two groups of patients treated with the success rate and wound closure time. Results The successful rates of treatment were 96.43% and 78.57% respectively in the two groups (P <0.05). The healing time of the wounds in the experimental group (16.17 ± 1.87) d and the experimental group (21.71 ± 3.95) d were statistically different Significance (P <0.01). Conclusions The emergency treatment of severely damaged skin and soft tissue injury should focus on the stable systemic condition of patients. The use of allogeneic skin to cover the wounds for second-stage wound repair can reduce the risk of emergency surgery, improve the success rate of treatment and shorten the treatment cycle.