关于利凡诺的精制方法,文献报道均采用无水乙醇重结晶,但收得率较低。为进一步提高其收得率,我们自1982年以来,设计了改良醇法、水溶丙酮析晶法、碱析法等三种精制方法。经多次实验,结果表明,水溶丙酮析晶法具有生产周期短、耗费溶剂少、产品色泽 About rivanol refining method, the literature reports were recrystallized from anhydrous ethanol, but the yield is low. In order to further improve its yield, since 1982, we have designed three refining methods: improved alcohol method, aqueous acetone crystallization method and alkaline analysis method. After many experiments, the results show that water-soluble acetone crystallization has the advantages of short production cycle, less solvent consumption, product color