人体小肠内的 pH 呈碱性时,可减少叶酸盐的吸收。临床上由于长期应用碳酸氢盐和胰酶治疗胰功能不全可导致叶酸缺乏。因小肠吸收不良而出现叶酸缺乏较常见,但胰液分泌不足很少引起叶酸缺乏。最近确诊而未经治疗的胰功能不全患者较治疗过的患者虽脂肪吸收较差,但血清叶酸水平却较高。以氚标记的蝶酰单谷氨酸进行叶酸吸收试验表明,胰功 The pH of the human small intestine is alkaline, can reduce the absorption of folate. Clinically due to long-term use of bicarbonate and pancreatic pancreatic insufficiency can lead to folic acid deficiency. Folic acid deficiency due to poor absorption of the small intestine is more common, but scarce secretion of pancreatic juice rarely causes folate deficiency. Recently diagnosed and untreated patients with pancreatic insufficiency than the treated patients despite poor fat absorption, but the high level of serum folate. Folic acid absorption assay with tritiated fluticasone mono glutamic acid showed pancreatic work