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目的:研究丹参注射液联合依拉普利对糖尿病肾病的临床疗效。方法:将2011—2012年在我院就诊的糖尿病肾病患者纳入研究,随机分为给予丹参注射液联合依拉普利治疗的观察组和仅给予依拉普利治疗的对照组,治疗前和治疗后4周时,分别检测两组患者的肾功能指标。结果:观察组患者的总有效率98.0%,整体治疗效果优于对照组;观察组患者的血肌酐、血尿素氮、24h尿蛋白均低于对照组,内生肌酐清除率高于对照组,差异有统计学意义(P<0.05)。结论:丹参注射液联合依拉普利治疗有助于提高治疗有效率、改善肾功能,具有较高的临床价值。
Objective: To study the clinical effect of Danshen injection combined with enalapril on diabetic nephropathy. Methods: Patients with diabetic nephropathy treated in our hospital from 2011 to 2012 were enrolled and randomly divided into observation group treated with Danshen injection combined with enalapril and control group treated with enalapril only. Before treatment and treatment After 4 weeks, the renal function of two groups were detected. Results: The total effective rate in observation group was 98.0%, and the overall treatment effect was better than that in control group. The serum creatinine, blood urea nitrogen and 24h urinary protein in observation group were lower than those in control group, and the creatinine clearance rate was higher than that in control group. The difference was statistically significant (P <0.05). Conclusion: Danshen injection combined with enalapril treatment can help to improve the treatment efficiency and improve renal function, with high clinical value.