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阿霉素(adriamycin,ADM)是蒽环类广谱抗肿瘤的抗生素,结构上与柔红霉素相似,但酮基侧链(14-C位)上多一个氢氧基团。其主要作用机制是通过嵌入二对相邻的碱基间,与DNA形成复合物,从而抑制DNA合成。由于抗瘤谱广,对各种恶性肿瘤有良好的效果。我院自1993年以来应用阿霉
Adriamycin (ADM) is an anthracycline-based broad-spectrum antitumor antibiotic that is structurally similar to daunorubicin but has one more hydroxyl group on the keto-side (14-C) side chain. Its main mechanism of action is to inhibit DNA synthesis by embedding two pairs of adjacent bases and forming complexes with DNA. Due to the broad anti-tumor spectrum, it has a good effect on various malignant tumors. Our hospital has applied M. oryzae since 1993