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有生育障碍的多囊卵巢综合征(PCOS)患者子宫内膜容受性受损是近年来生殖领域研究的热点,研究发现子宫内膜的厚度、容积及内膜下血流的减少,子宫内膜间质的异常、性激素及其受体的不均衡表达,以及子宫内膜容受性标志物的降低等均可导致子宫内膜容受性受损。本文将多囊卵巢综合征患者的子宫内膜容受性特点从超声影像学、病理组织学特点、性激素受体及着床期分子表达、基因芯片、转录组学等五个方面来阐述。
Endometrial receptivity in patients with polycystic ovary syndrome (PCOS) with reproductive failure is a hotspot in the field of reproductive research in recent years. Studies have found that the thickness and volume of endometrium and the decrease of blood flow in the intima, Membrane abnormalities, imbalance of sex hormones and their receptors, as well as the reduction of endometrial receptivity markers may lead to impaired endometrial receptivity. In this paper, the characteristics of endometrial receptivity of polycystic ovary syndrome patients from five aspects: ultrasound imaging, histopathological features, sex hormone receptors and implantation of molecular expression, gene chip, transcriptomics and so on.