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先天性长QT间期综合征、电解质紊乱、应用数种抗心律失常药后、急性心肌梗塞后,QT间期的延长关系到险恶室性心律失常和心源性猝死的危险性增加。已知QT间期的时间取决于心动周期的长度,以往临床最常用Bazett在1920年提出的QT校正公式(QT_e=QT(RR)~(1/2)),但此公式在当时仅是来自对于39例年轻受试者的推导。近来人们已发现,Batett提出的QT校正公式在精确性方面存在一定的问题。本文为了评价心率对QT的影响,作者在Framingham心脏研究中心测量了5018例平均年龄44岁、无冠心病受试者的最基本心电图(男2 239例,女2779例,年龄范围28～62岁)。为按照RR周期长度而校正QT,并研究了一种直线回归模型。把受试者进一步地进行RR间距性别差异的亚分组,对照QT间期、Bazett氏校正QT间期(QT_e)和直线校正QT间期(QT_(LC)).
Congenital long QT syndrome, electrolyte imbalance, the application of several anti-arrhythmic drugs, acute myocardial infarction, QT prolongation of the relationship between the risk of ventricular arrhythmias and increased risk of sudden cardiac death. It is known that the QT interval depends on the length of the cardiac cycle. In the past, QT correction formula (QT_e = QT (RR) ~ (1/2)) proposed by Bazett in 1920 was most commonly used in clinical practice. However, Derivation of 39 young subjects. Recently, it has been found that the QT correction formula proposed by Batett has certain problems in terms of accuracy. To evaluate the effect of heart rate on QT, the authors measured 5018 patients with a mean age of 44 years at the Framingham Heart Institute, the most basic ECG without coronary heart disease (2 239 males and 2779 females, ranging in age from 28 to 62 years ). To correct the QT according to the RR period length, a linear regression model was studied. Subjects were further subdivided by gender differences in RR interval, control QT interval, Bazett’s QT interval (QT_e), and QT interval (QT_ (LC)).