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70年代以来男性避孕的研究已取得了令人鼓舞的进展。归纳男性避孕方法主要是通过下述四个途径:一、干扰生精器官,破坏精子生成(一)减少 LH-RH 对垂体的作用:现已明确 LH-RH 是广肽激素,能刺激产生精子所必须的 FSH 和 LH 的释放。因此,利用 LH-RH 的类似物与 LH-RH 在垂体内竞争受体,破坏刺激 FSH 和 LH 的分泌,达到减少、阻断和破坏生精作用,这一研究已在广泛进行并得到了可喜的结果。Hearn 等利用 LH-RH 类似物控制垂体中促性腺激素的
Research on male contraception has made encouraging progress since the 1970s. Summarize the male contraceptive method is mainly through the following four ways: First, interfere with spermatogenesis, destruction of sperm production (A) to reduce the LH-RH on the role of the pituitary: It has been clear that LH-RH is a peptide hormone, can stimulate the production of sperm Required FSH and LH release. Thus, the use of LH-RH analogs and LH-RH to compete with receptors in the pituitary gland to disrupt the secretion of FSH and LH, thereby reducing, blocking and destroying the spermatogenesis, has been extensively studied and is promising the result of. Hearn et al use LH-RH analogs to control pituitary gonadotropin