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目的探讨1.5T磁共振弥散加权成像在胃癌诊断中的应用价值。方法 36例胃部病变患者,其中胃癌分化好组11例,胃癌分化差组19例,良性病变组6例,同期健康成人志愿者10名为对照组,4组均行磁共振弥散加权成像,采用自旋回波/平面回波序列,测量胃壁在表观弥散系数(apparent diffusion coefficient,ADC)图上的ADC值,并进行比较。结果4组胃壁ADC值比较差异有统计学意义(F=26.76,P<0.05);根据ROC曲线,以ADC值<1.36×10-3 mm2/s为标准,磁共振弥散加权成像诊断胃癌的敏感性为87.5%,特异性为90.0%。结论磁共振弥散加权成像对进展期胃癌有较高敏感性和特异性,ADC值有助于病变的诊断和鉴别诊断。
Objective To investigate the value of 1.5T magnetic resonance diffusion-weighted imaging in the diagnosis of gastric cancer. Methods Thirty-six patients with gastric lesions, including 11 well-differentiated gastric cancer group, 19 poorly differentiated gastric cancer group, 6 benign lesion group and 10 healthy adult volunteers at the same period, were included in the study. All of the 4 groups were treated with MR diffusion-weighted imaging, The ADC values of the gastric wall on the apparent diffusion coefficient (ADC) plot were measured and compared using spin echo / planar echo sequences. Results There was significant difference in ADC value of gastric wall between the four groups (F = 26.76, P <0.05). According to the ROC curve, the value of ADC value <1.36 × 10-3 mm2 / s was the standard of MR diffusion weighted imaging in the diagnosis of gastric cancer The sex was 87.5% and the specificity was 90.0%. Conclusion MR diffusion weighted imaging of advanced gastric cancer have a higher sensitivity and specificity, ADC value contribute to the diagnosis and differential diagnosis of lesions.