不对称催化是由潜手性反应物合成光活性化合物的有效途径,α,β-不饱和氨基酸的氢化立体选择性已达90％以上,L-Dopa的工业化生产则标志着不对称催化氢化开始走向实际应用。高选择性的催化剂一般是一价铑的手性双膦配体络合物,其中DIOP[2,3-O-异丙叉- Asymmetric catalysis is an effective way to synthesize photoactive compounds from latent chiral reactants. The hydrogenation stereoselectivity of α, β-unsaturated amino acids has reached more than 90%. The industrial production of L-Dopa marks the beginning of asymmetric catalytic hydrogenation Go to practical application. Highly selective catalysts are generally monovalent rhodium chiral bisphosphine ligand complexes where DIOP [2,3-O-isopropylidene-