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目的分析保儿宁联合布地奈德同步治疗小儿变应性鼻炎并哮喘的疗效及安全性。方法选取2015年7月—2016年7月诊疗的88例小儿变应性鼻炎并哮喘患儿,随机分为研究组和对照组各44例,对照组行布地奈德治疗,研究组行布地奈德联合保儿宁治疗,比对两组治疗后哮喘症状与鼻炎症状评分、T淋巴细胞亚群以及不良反应情况,数据进行统计学分析,P<0.05为差异有统计学意义。结果治疗后研究组哮喘症状与鼻炎症状评分均低于对照组(t=6.015、9.258,均P<0.05),T淋巴细胞亚群得分均优于对照组(均P<0.05),不良反应总发生率4.54%少于对照组43.18%(χ~2=18.075,P<0.05),差异均有统计学意义。结论小儿变应性鼻炎并哮喘行布地奈德联合保儿宁治疗可改善哮喘症状与鼻炎症状,且不良反应少,药物安全性高,值得推广。
Objective To analyze the efficacy and safety of Paulinen combined with budesonide in the treatment of children with allergic rhinitis and asthma. Methods 88 pediatric patients with allergic rhinitis and asthma diagnosed and treated from July 2015 to July 2016 were randomly divided into study group and control group, 44 cases in each group. The control group received budesonide, De combined with Pauline rather treatment than the two groups after treatment of asthma symptoms and rhinitis symptom score, T lymphocyte subsets and adverse reactions, the data were statistically analyzed, P <0.05 for the difference was statistically significant. Results The symptom scores of asthma and rhinitis in the study group were lower than those in the control group (t = 6.015, 9.258, all P <0.05), and the score of T lymphocyte subgroup was better than that of the control group (all P <0.05) The incidence was 4.54% less than the control group 43.18% (χ ~ 2 = 18.075, P <0.05), the differences were statistically significant. Conclusions The treatment of allergic rhinitis and asthma in children with Budesonide combined with Bao’erning can ameliorate the symptoms of asthma and the symptoms of rhinitis with less side effects and high drug safety. It is worth to be popularized.