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为研究下肢深静脉血栓形成与肺栓塞发病之间的关系，对１７１例临床诊断为下肢静脉病变者，使用９９ｍＴｃ大颗粒聚合白蛋白（ＭＡＡ）进行下肢深静脉和肺灌注显像。其中１０例行Ｘ线下肢静脉造影，１８例肺栓塞患者行ＤＳＡ检查，１５例行ＭＲＩ检查。结果：下肢深静脉及肺灌注显像可见１７１例下肢静脉病变患者中有９８例（５７３％）合并肺栓塞；９８例肺栓塞患者中股静脉以上梗阻为７９例，占８０６％。与ＤＳＡ、ＭＲＩ和Ｘ线下肢静脉造影检查的符合率分别为８８９％、８６７％和９００％。故核素下肢深静脉显像结合肺灌注显像是诊断下肢深静脉血栓和肺动脉栓塞的有效方法。
In order to study the relationship between deep venous thrombosis of lower extremity and the incidence of pulmonary embolism, deep venous and perfusion imaging of lower extremities was performed on 171 patients with clinically diagnosed venous lesions of lower extremities using 99mTc-MAA. X-ray venography was performed in 10 cases, DSA in 18 cases and MRI in 15 cases. Results: There were 98 cases (573%) with pulmonary embolism in 171 cases of lower extremity venous diseases and 79 cases (98.6%) in 98 cases of pulmonary embolism with pulmonary vein perfusion imaging. . The coincidence rates with DSA, MRI and X-ray venography were 889%, 867% and 900% respectively. Therefore, deep vein nuclide imaging combined with pulmonary perfusion imaging is an effective method for the diagnosis of deep vein thrombosis and pulmonary embolism.