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目的调查内蒙古林业总医院口服抗高血压药应用情况及发展趋势,为临床合理、经济用药提供参考。方法采用世界卫生组织推荐的限定日剂量(DDD)方法,对内蒙古林业总医院2007-2009年口服抗高血压药的销售金额、用药频度(DDDs)、日均费用(DDC)以及销售金额与DDDs排序列前10位的药品等进行统计分析。结果 2007-2009年内蒙古林业总医院抗高血压药品种、数量及销售金额呈逐年上升趋势。应用抗高血压药主要包括CCB、ACEI、β受体阻滞剂、利尿剂、ARB。3年中CCB的销售金额稳居各年度抗高血压药的首位。ACEI的DDDs连续3年最高,CCB和β受体阻滞剂的DDDs均居中。销售金额排序列在前10位的药品始终占抗高血压药总销售金额的90%以上。硝苯地平销售金额连续3年位列第1,替米沙坦从第6位上升至第2位,氨氯地平从第10位上升至第4位,厄贝沙坦作为新型抗高血压药,销售金额正呈逐年上升趋势。美托洛尔和非洛地平位次相对稳定。3年间DDDs排序列第1位的是卡托普利,螺内酯DDDs较高。DDC最高的是硝苯地平缓释片,但是其DDDs有所下降,非洛地平和氨氯地平的DDC也较高,DDC最低的是卡托普利和尼莫地平。结论该院抗高血压药物应用基本合理。
Objective To investigate the application situation and development trend of oral antihypertensive drugs in Inner Mongolia Forestry General Hospital and provide references for clinical rational and economical use. Methods The recommended daily dose (DDD) method recommended by the World Health Organization (WHO) was used to estimate the sales amount, frequency of DDDs, DDC and the sales amount of oral antihypertensive drugs in Inner Mongolia Forestry General Hospital from 2007 to 2009. DDDs ranked the top 10 drugs for statistical analysis. Results 2007-2009 Inner Mongolia Forestry General Hospital antihypertensive drugs varieties, the amount and sales volume showed an upward trend year by year. Antihypertensive drugs include CCB, ACEI, beta blockers, diuretics, ARB. CCB’s sales volume in three years ranked the first place in the annual anti-hypertensive drugs. The DDDs of ACEI were the highest for 3 years in a row, and the DDDs of CCB and β-blockers were both middle. Sales ranked top 10 drugs always accounted for more than 90% of the total sales of anti-hypertensive drugs. Nifedipine sales amount ranked No. 1 for three consecutive years, telmisartan rose from No. 6 to No. 2, amlodipine rose from No. 10 to No. 4, irbesartan as a new antihypertensive drug , The amount of sales is rising year by year. Metoprolol and felodipine were relatively stable. DDDs ranked first in three years is captopril, spironolactone DDDs higher. The highest DDC was nifedipine sustained-release tablets, but its DDDs decreased. The DDC of felodipine and amlodipine was also higher. The lowest DDC was captopril and nimodipine. Conclusion The hospital antihypertensive drugs basically reasonable.