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发达国家采用高接种率的2针常规免疫或2针常规免疫辅以初始强化免疫和后续免疫,使麻疹得以控制并进入消除阶段。中国人口多、密度大,政府投入难于满足1~14岁儿童在1个月内统一的初始强化免疫和8月龄~4岁儿童后续免疫所需的疫苗和注射器,以及对农村尤其是边远地区上门接种的费用;分片强化免疫又不能控制当年未作强化地区的疫情。以县为单位将历年疫情进行分析,对高危县作预测甄别和局部强化免疫,这种既遏制疫情又形成成片免疫屏障的甄别普种、零存整取策略,是发展中国家尤其是不发达地区首选的控制麻疹与消除策略。
In developed countries, 2-gauge conventional immunization or 2-gauge routine immunization with high inoculation rate supplemented with initial intensive immunization and subsequent immunization led to the control of measles and the elimination phase. China has a large population and a large population. It is difficult for the government to invest in vaccines and syringes that are required for uniform immunization of 1-to-14-year-old children and follow-up immunizations of children aged 8 months to 4 years old within 1 month. In addition, Inoculation costs; fragmentation enhanced immunity can not control the year did not strengthen the area of the epidemic. County epidemic situation over the years to conduct an analysis of high-risk counties for the screening and local fortified immune system, which not only curb the outbreak but also form a piece of immune barrier screening common stock, zero stocking strategy is not particularly in developing countries Controlled measles and elimination strategies in developed regions.