有更多证据证实肿瘤坏死因子(TNF)a与脓毒性休克有关.Chiron公司和纽约两所大学的研究人员在注射致死量大肠杆菌之前,给狒狒注射抗TNF单克隆抗体.在注射菌体前2小时接受抗体的3只狒狒完全得以防止休克,避免重要器官机能障碍,应激性激素的释放和死亡.未接受TNF抗体的6只动物在注射 There is more evidence that tumor necrosis factor (TNF) a is associated with septic shock, and researchers at both Chiron and New York universities injected baboons with anti-TNF mAbs before injecting the lethal dose of E. coli Three baboons receiving antibodies at 2 hours were completely protected against shock, avoiding vital organ dysfunction, release of stress hormones, and death.6 Six animals that did not receive TNF antibody were injected