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目的探索磁敏感加权成像(SWI)技术在诊断新生儿缺血缺氧性脑病(HIE)中的应用价值。方法收集2014年1月-2016年2月在南方医科大学深圳医院儿科,接受治疗的HIE的新生儿患者66例并用1.5 T超导型MR扫描仪对所有患儿进行颅脑检查,检查前30 min需进行灌肠或者服用10%水合氯醛将患儿催眠。在常规MRI(DWI、T1WI以及T2WI)横向扫描的基础上加用SWI横向扫描。将MRI与SWI对患儿检出率及病灶范围进行比较分析。结果 SWI诊断脑出血病灶的数目、病灶范围以及病变部位清晰程度明显优于DWI、T1WI以及T2WI的检测结果差异有统计学意义(P<0.05),结论 SWI技术诊断新生儿HIE在检测出血病灶数目及范围方面中具有较高的临床应用价值,临床上可推荐患者使用。
Objective To explore the value of magnetic susceptibility weighted imaging (SWI) in the diagnosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods Sixty-six neonates with HIE who underwent treatment in the Department of Pediatrics, Shenzhen Medical College of Shenzhen Medical University from January 2014 to February 2016 were enrolled. All children underwent MRI examination with a 1.5 T superconductive MR scanner. min need to enema or take 10% chloral hydrate hypnosis in children. Based on conventional MRI (DWI, T1WI and T2WI) lateral scan, an additional SWI scan was applied. MRI and SWI detection rate of children and lesion range comparative analysis. Results The numbers of SWI, the range of lesion and the clarity of lesion were significantly better than those of DWI. There was significant difference between T1WI and T2WI (P <0.05). Conclusion The SWI diagnosis of neonatal HIE in detecting the number of hemorrhagic lesions And the range of high clinical value, the clinical recommendation of patients.