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目的：探讨腰硬脊膜外压（ＩＳＥＤＰ）与脑室内压（ＩＶＰ）之间关系，了解ＩＳＥＤＰ能否监测颅内压。方法：选择５例颅脑疾病继发脑积水患者，采用ＬＮＰ－Ⅰ型经腰硬脊膜外腔颅内压监护仪和ＬＹ－Ⅱ型脑室内压监护仪进行持续监测，病人取水平侧卧体位，以每隔５分钟记录ＩＶＰ和ＩＳＥＤＰ压力数据一次，期间多次重复操作ＬＮＰ－Ⅰ型监护仪与ＩＶＰ进行对照，同时观察临床症状，压力波形及颅高压时间断行脑室引流时二者变化。最终将所有数据输入电脑采用线性回归方法统计。结果：持续ＩＶＰ和ＩＳＥＤＰ二者统计相关系数为０．９８８，Ｐ＜０．０１，总体压力／时间呈平行走行趋势；多次重复操作二者相关系数为０．９５５，Ｐ＜０．０１。在ＩＶＰ增高期间，ＩＳＥＤＰ出现Ｂ波，间断引流脑室ＣＳＦ时发现其逐渐下降过程，持续描记的波形、波幅与ＩＶＰ变化和临床症状相吻合。结论：ＩＳＥＤＰ能准确地反映颅内压变化，持续监测稳定性好。但对脑疝或椎管梗阻者应用受限。
Objective: To investigate the relationship between ISEDP and IVP and to investigate whether ISEDP can monitor intracranial pressure. Methods: Five patients with hydrocephalus secondary to craniocerebral disease were enrolled in this study. LNP-Ⅰ type of extracavitary epicardial intracranial pressure monitor and LY-Ⅱ type of intraventricular pressure monitor were used for continuous monitoring. Lying position to record IVP and ISEDP pressure data once every 5 minutes during repeated operation LNP-Ⅰ type of monitor and IVP were compared, while observing the clinical symptoms, pressure waveforms and cranial hypertension when the line of ventricular drainage changes both changes . Finally, all the data input into the computer using linear regression method of statistics. Results: The statistical correlation coefficient of continuous IVP and ISEDP was 0.988, P <0.01, and the overall pressure / time showed a parallel trend. The correlation coefficient of multiple repeated operation was 0.955, P <0.01. During the increase of IVP, B wave was found in ISEDP, and the gradual descending process of CSF was found in intermittent drainage of ventricle. The waveform and amplitude of persistent trace coincided with the changes of IVP and clinical symptoms. Conclusion: ISEDP can accurately reflect the changes of intracranial pressure, continuous monitoring of good stability. However, hernia or spinal canal obstruction is limited.