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我院研究治疗肿瘤已有10余年,总结出地塞米松在肿瘤病中有许多新用途。现简述如下:1.与镇静止吐药联合止吐 大部分抗肿瘤药物都有恶心呕吐的副反应。呕吐虽为一种保护性反应,但严重频繁的呕吐,造成病人厌食,加重病人痛苦,也会引起体内水、电解质和酸碱平衡紊乱。为避免上述反应,化疗前半小时给予胃复安20mg,苯海拉明40mg肌肉注射,地塞米松10mg静脉推注,可有效防治化疗后恶心及呕吐,减少病人的痛苦。2.与维生素C、利多卡因联合治疗化疗药物外渗 绝大多数需静脉用的化疗药物,对肌肉组织有刺激性,若不慎渗漏到血管外,可引起局部组织红肿热痛,严重者
Our hospital has been researching and treating cancer for more than 10 years. It has been concluded that dexamethasone has many new uses in oncology. Here are brief descriptions as follows: 1. Joint antiemetic with quiescent antiemetic Most anti-cancer drugs have side effects of nausea and vomiting. Although vomiting is a protective reaction, severe and frequent vomiting causes the patient to anorexia and aggravate the patient’s pain. It can also cause disturbances in the body’s water, electrolyte and acid-base balance. To avoid these reactions, metoprolol (20 mg), diphenhydramine (40 mg) and intramuscular injection of dexamethasone (10 mg) were given half an hour before chemotherapy, which can effectively prevent and treat nausea and vomiting after chemotherapy and reduce patient’s pain. 2. In combination with vitamin C and lidocaine, the majority of chemotherapeutic drugs used for extravasation of chemotherapeutic drugs need to be administered intravenously. They are irritating to muscle tissue. If they inadvertently leak into blood vessels, they can cause local tissue swelling and thermal pain. By