论文部分内容阅读
应用单向免疫扩散法测定了流行性出血热(EHF)患者的7种补体成份和血浆素原(Pg).结果表明,CT脂酶抑制剂在少尿期、多尿期和恢复期均高于正常(P<0.01);补体C_1q在多尿期高于正常(P<0.01);补体C_4在发热期和少尿期低于正常(P<0.01),以后逐渐恢复正常;补体C_3,C_5和C_9的变化与C_4相似;B因子在少尿期低于正常(P<0.01),在多尿期高于正常(P<0.05);Pg始终高于正常水平但在少尿期有回降.说明EHF患者不仅有补体经典途径的识别阶段、活化阶段和膜攻击阶段的变化,而且亦有旁路激活,其活化程度与病情有关.
Seven kinds of complement components and plasminogen (Pg) in patients with epidemic hemorrhagic fever (EHF) were determined by one-way immunodiffusion method.The results showed that CT lipase inhibitors were high in oliguria period, polyuria period and recovery period (P <0.01). Complement C_1q was higher than normal in polyuria (P <0.01). Complement C_4 was lower than normal in febrile stage and oliguria (P <0.01), and then returned to normal gradually. Complement C_3 and C_5 And C_9 were similar to those of C_4; factor B was lower than normal in oliguria (P <0.01) and higher than normal in polyuria (P <0.05); Pg was always higher than normal level but decreased in oliguria EHF patients not only have the identification of the classical pathway of complement, activation and membrane attack phase changes, but also by-pass activation, the degree of activation of the disease.