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米非司酮(Mifepristone,简称RU486,化学名称17β-羟11-β-[4-二甲胺苯基]-172-[1-丙妾炔基]雌甾-4、9-双烯-3-酮),它是世界上第一个合成的强效抗孕激素药物,其作用于孕酮受体水平,通过与孕激素竞争受体而达到抗孕激素的药理作用。十多年来RU486已成为计划生育领域中的科研热点,尤其是RU486合并PG药物抗早孕的成功,可成为人类终止早孕方法上的一次革命。RU486作为临床抗早孕药物已在我国注册,
Mifepristone (abbreviation: RU486, chemical name: 17β-hydroxy 11- β- [4-dimethylaminophenyl] -172- [1-cumylthynyl] estra-4,9- - ketone), which is the world’s first potent antiprogestational hormone drug that acts on progesterone receptor levels and competes with progesterone for the pharmacological effects of antiprogestins. For more than a decade, RU486 has become a research hotspot in the field of family planning. In particular, the success of RU486 in combination with PG drugs in anti-early pregnancy can be a revolution in the termination of early pregnancy. RU486 as a clinical anti-pregnancy drug has been registered in our country,