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肾小球硬化、肾小管间质纤维化是多种肾脏疾病的最终结果。肾固有细胞增殖、细胞外基质 (ＥＣＭ )异常增多为其主要特点。外源性前列腺素Ｅ(ＰＧＥ)具有抗凝以外的多种生物活性 ,为此 ,作者就前列腺素Ｅ在延缓肾纤维化中的作用作一综述。1 来源与肾内分布前列腺素是具有重要生
Glomerulosclerosis and tubulointerstitial fibrosis are the end result of many kidney diseases. Renal intrinsic cell proliferation, extracellular matrix (ECM) abnormal increase of its main features. Exogenous prostaglandin E (PGE) has many biological activities besides anticoagulation. Therefore, the author reviews the role of prostaglandin E in delaying renal fibrosis. 1 source and distribution of prostaglandins within the kidney is of important importance