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目的观察辛伐他汀(舒降之)治疗高脂血症的临床疗效。方法对62例高脂血症患者给予口服辛伐他汀20mg/d,治疗8周。治疗前、后分别测定胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)等。结果治疗前后血脂水平比较差异有统计学意义(P均<0.01),治疗后血脂降低效果明显。服药期间部分患者出现消化道反应及一过性ALT、AST增高等不良反应。结论辛伐他汀调脂疗效好,不良反应少。
Objective To observe the clinical efficacy of simvastatin (SHR) in the treatment of hyperlipidemia. Methods 62 patients with hyperlipidemia were given simvastatin 20mg / d for 8 weeks. Cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) were measured before and after treatment. Results Before and after treatment, there was significant difference in the level of serum lipids (P <0.01), and the effect of lowering blood lipids was obvious after treatment. Some patients during medication gastrointestinal reactions and transient ALT, AST increased adverse reactions. Conclusions Simvastatin is effective in regulating lipids and has few adverse reactions.