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我所试制通脉冲剂有理气、活血、化瘀、止痛、宁心安神的作用,据临床组观察,对气滞血瘀型冠心病有一定疗效。药理组用其同样的配方制成的注射液作动物实验,证明:①增加小白鼠耐缺氧的能力;②增加离体豚鼠心脏冠脉流量和心脏收缩力的作用;③对大白鼠急性缺血也有一定的保护作用。在此基础上我们探索通脉注射液对大白鼠心肌坏死有无保护作用。现将实验结果总结如下。一、材料和方法本实验用的通脉注射液系本所植化组
I have experimented with pulsating agents with rational gas, promoting blood circulation, resolving phlegm, relieving pain, and reassuring the nerve. According to clinical observation, it has a certain effect on qi stagnation and blood stasis type coronary heart disease. The pharmacological team used its injections made of the same formula as animal experiments to prove: (1) increasing the ability of mice to tolerate hypoxia; (2) increasing the effect of coronary artery flow and cardiac contractility in isolated guinea pig hearts; and (3) acute deficiency of rats. Blood also has a certain protective effect. On this basis, we explore whether Tongmai injection has no protective effect on myocardial necrosis in rats. The experimental results are summarized below. I. Materials and methods Tongmai injection used in this experiment was phytochemical group