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目的探讨乳腺鳞状细胞癌的临床病理特征及诊断和鉴别诊断。方法对4例乳腺鳞状细胞癌进行光镜观察并文献复习。结果乳腺鳞状细胞癌好发于中老年人,平均年龄53岁。大体表现多为囊实性;镜下肿瘤均由多边形大细胞构成不规则的实性团索,细胞核核仁明显,可见不同程度的角化,细胞间存在明显的细胞间桥。结论乳腺鳞状细胞癌罕见,需要与乳腺腺鳞癌、血管肉瘤和浸润性导管癌中的鳞状上皮化生等鉴别。
Objective To investigate the clinicopathological features, diagnosis and differential diagnosis of breast squamous cell carcinoma of the breast. Methods Four cases of breast squamous cell carcinoma were observed under light microscope and reviewed by literature. Results of breast squamous cell carcinoma occur in the elderly, with an average age of 53 years. Most of the tumors showed cystic solidity. Microscopically, the tumors were composed of polygonal macrophages with irregular corporeal cords. The nucleoli of the nucleus were obvious, with varying degrees of keratosis and obvious intercellular bridges between the cells. Conclusions Breast squamous cell carcinoma is rare and needs to be differentiated from adenosquamous carcinoma of the breast, squamous metaplasia of angiosarcoma and invasive ductal carcinoma.