目的　评估集束电极射频 (radiofrequency ,RF)治疗肝癌的临床疗效及适应证。 方法　复习连续的2 5 0例肝癌病人经多弹头射频治疗的临床资料 ,比较治疗前后瘤体内血供状况、肿瘤大小、AFP值变化及病人自觉症状的改善情况。结果　AFP值术后 1周内下降者占 5 0 % ,病人自觉症状明显改善。瘤体直径 <5cm的肝癌 ,其术后 1～ 6个月大部分瘤体血供消失 ,瘤体缩小 ,甚至消失。个别瘤体复发经再次射频治疗得到控制。直径>5cm的肝癌 ,配合以介入栓塞治疗 ,多数瘤体缩小。继发性肝癌 ,就瘤体而言 ,射频治疗术后大部分瘤体缩小得到控制。结论　B超引导下多弹头射频治疗肝癌近期疗效确切 ,而且满意。 Objective To evaluate the clinical efficacy and indications of radiofrequency (RF) in the treatment of hepatocellular carcinoma with a collecting electrode. Methods The clinical data of continuous multi-warhead radiofrequency treatment of 250 consecutive patients with liver cancer were reviewed. The blood supply, tumor size, AFP value and improvement of patient’s subjective symptoms before and after treatment were compared. Results The AFP value decreased by 50% within 1 week after operation, and the patient’s subjective symptoms improved significantly. In tumors with a tumor diameter <5cm, the blood supply of most tumors disappeared within 1 to 6 months after surgery, and the tumors shrinked or even disappeared. Recurrence of individual tumors was controlled by radiofrequency treatment again. Liver cancer with a diameter of >5cm was treated with interventional embolization, and most of the tumors shrank. For secondary liver cancer, in terms of tumors, most of the tumor shrinkage after radiofrequency treatment is controlled. Conclusion The short-term therapeutic effect of multi-warhead radiofrequency ablation guided by B-ultrasound is definite and satisfactory.